NEW YORK (AP) — Donovan Clingan, Tristen Newton and top overall seed UConn overwhelmed an undermanned Northwestern team 75-58 on Sunday night to sail into the Sweet 16 of the NCAA Tournament.

Newton had 20 points and 10 assists, and Clingan finished with 14 points, 14 rebounds and eight blocks as the Huskies (33-3) led wire-to-wire and became the first defending national champions to reach the regional semifinals since Duke in 2016.

EAST REGION

NO. 24 SAN DIEGO STATE 85, YALE 57

SPOKANE, Wash. (AP) — Jaedon LeDee had 26 points and nine rebounds, Darrion Trammell added 18 points and fifth-seeded San Diego State used a fast start to overwhelm 13th-seeded Yale and rolled to a win in the second round of the NCAA Tournament.

MIDWEST REGION

NO. 3 PURDUE 106, UTAH STATE 67

INDIANAPOLIS (AP) — Zach Edey had 23 points and 14 rebounds, and No. 1 seed Purdue cruised into the Sweet 16 by pounding eighth-seeded Utah State with an impressive offensive performance in the second round of the NCAA Tournament.

SOUTH REGION

NO. 2 HOUSTON 100, TEXAS A&M 94, OT

MEMPHIS, Tenn. (AP) — Emanuel Sharp started overtime with a 3-pointer that put top-seeded Houston ahead to stay as the Cougars advanced to the Sweet 16 back in Texas by topping ninth-seeded Texas A&M.

NO. 8 MARQUETTE 80, COLORADO 77

INDIANAPOLIS (AP) — Tyler Kolek had 21 points and 11 assists, and David Joplin made two free throws with 7.4 seconds left to help Marquette finally put away Colorado.

NO. 13 DUKE, 93, JAMES MADISON 55

NEW YORK (AP) — Jared McCain scored 22 of his 30 points in the first half and set a Duke record for an NCAA Tournament game with eight 3-pointers as the Blue Devils ended 12th-seeded James Madison’s dream season with a second-round victory.

WEST REGION

CLEMSON 72, NO. 14 BAYLOR 64

MEMPHIS, Tenn. (AP) — Chase Hunter had 20 points and six assists, and No. 6 seed Clemson held off third-seeded Baylor for a victory in the second round of the NCAA Tournament.

NO. 19 ALABAMA 72, GRAND CANYON 61

SPOKANE, Wash. (AP) — Mark Sears had 26 points and 12 rebounds, Mouhamed Dioubate scored all nine of his points in the final 5 1/2 minutes, and fourth-seeded Alabama used a late surge to beat No. 12 seed Grand Canyon.

Sears carried the Crimson Tide (23-11) for the better part of 35 minutes before getting some unexpected help from Dioubate. The 6-foot-7 freshman scored more than nine points only twice all season but made the most of his chance to contribute in the final minutes of a physical game with Alabama in foul trouble and without starter Latrell Wrightsell Jr., who suffered a head injury in the first half.

Alabama advanced to the Sweet 16 for the 10th time overall and third time in the last four seasons under coach Nate Oats. The Crimson Tide will play in a regional semifinal in consecutive seasons for the first time since 1990-91; last year, Alabama was a No. 1 seed and fell to eventual national runner-up San Diego State.

This time, it’ll be the Tide trying to take down top-seeded North Carolina on Thursday in a West Region semifinal Los Angeles.

Sears made 8 of 18 shots and cheekily waved goodbye in the final seconds to the Grand Canyon “Havocs” fans who filled Spokane Arena. Dioubate also grabbed five rebounds in his 12 minutes and played solid defense on Grand Canyon star Tyon Grant-Foster.

Grant-Foster scored 29 points, one off his career high, but didn’t score in the final 4:40. The Lopes shot 32%, including a brutal 3 of 17 to begin the game. Grand Canyon (31-4) also couldn’t find anything from beyond the 3-point arc, going 2 of 20.